San Francisco 49ers: Schedule
| Home Team | Away Team | Home Score | Away Score | W - L | Game Date |
|---|---|---|---|---|---|
| Pittsburgh Steelers | San Francisco 49ers | 7 | 30 | 1 - 0 | 2023-09-10 |
| Los Angeles Rams | San Francisco 49ers | 23 | 30 | 2 - 0 | 2023-09-17 |
| San Francisco 49ers | New York Giants | 30 | 12 | 3 - 0 | 2023-09-22 |
| San Francisco 49ers | Arizona Cardinals | 35 | 16 | 4 - 0 | 2023-10-01 |
| San Francisco 49ers | Dallas Cowboys | 42 | 10 | 5 - 0 | 2023-10-09 |
| Cleveland Browns | San Francisco 49ers | 19 | 17 | 5 - 1 | 2023-10-15 |
| Minnesota Vikings | San Francisco 49ers | 22 | 17 | 5 - 2 | 2023-10-24 |
| San Francisco 49ers | Cincinnati Bengals | 17 | 31 | 5 - 3 | 2023-10-29 |
| Jacksonville Jaguars | San Francisco 49ers | 3 | 34 | 6 - 3 | 2023-11-12 |
| San Francisco 49ers | Tampa Bay Buccaneers | 27 | 14 | 7 - 3 | 2023-11-19 |
| Seattle Seahawks | San Francisco 49ers | 13 | 31 | 8 - 3 | 2023-11-24 |
| Philadelphia Eagles | San Francisco 49ers | 0 | 0 | 8 - 3 | 2023-12-03 |
| San Francisco 49ers | Seattle Seahawks | 0 | 0 | 8 - 3 | 2023-12-10 |
| Arizona Cardinals | San Francisco 49ers | 0 | 0 | 8 - 3 | 2023-12-17 |
| San Francisco 49ers | Baltimore Ravens | 0 | 0 | 8 - 3 | 2023-12-26 |
| Washington Commanders | San Francisco 49ers | 0 | 0 | 8 - 3 | 2023-12-31 |
| San Francisco 49ers | Los Angeles Rams | 0 | 0 | 8 - 3 | 2024-01-07 |